Kinetic properties of 99mTc-Q12 in canine myocardium.
نویسندگان
چکیده
منابع مشابه
Canine Myocardium
Background I'Tc-Q12 is a new Tc(III) perfusion imaging agent that permits prompt myocardial visualization in humans. We postulated that 9'Tc-Q12 myocardial activity is related to actual myocardial blood flow during conditions of myocardial ischemia and pharmacological coronary artery vasodilation and that 99'Tc-Q12 shows little or no myocardial redistribution as long as 4 hours after intravenou...
متن کاملVariability and reproducibility of rubidium-82 kinetic parameters in the myocardium of the anesthetized canine.
UNLABELLED Kinetic analysis of 82Rb dynamic PET data produces quantitative measures which could be used to evaluate ischemic heart disease. These measures have the potential to generate objective comparisons of different patients or the same patient at different times. To achieve this potential, it is essential to determine the variability and reproducibility of the kinetic parameters. METHOD...
متن کاملCanine Ventricular Myocardium In Vivo
a square array of 64 closely spaced electrodes and a computer-assisted acquisition and analysis system. Amiodarone caused a rate-dependent decrease in conduction velocity with a slightly greater effect in the longitudinal direction of propagation. Rate-related depression of conduction velocity developed rapidly after abrupt shortening of the pacing cycle length; 67% of the change occurred betwe...
متن کاملBarriers in Anisotropic Canine Myocardium
We developed a computer model of the interaction of impulse propagation with anatomic barriers in uniformly anisotropic tissue. Its predictions were confirmed experimentally by using an in vitro cut to create a 6x 1-mm anatomic barrier in 12 canine epicardial strips. The model predicted that long, thin barriers located parallel to the direction of impulse propagation would have little effect in...
متن کاملisoprenaline-stimulated canine myocardium
Objective: We have previously demonstrated that myocardium is capable of down-regulating its 0, requirements and thus avoiding ischaemia when 0, supply is limited. The present study tested the hypothesis that endogenous adenosine produced this protective response when 0, supply was decreased by moderate coronary hypoperfusion or moderate coronary hypoxaemia. Methods: In anaesthetised dogs, hear...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Circulation
سال: 1994
ISSN: 0009-7322,1524-4539
DOI: 10.1161/01.cir.89.3.1291